1. Molecular Biophysics
Molecular Dynamics (MD) simulations and Quantum Mechanical (QM) calculations are used in
studying the conformations of biologically important oligosaccharides and the binding specificity
of proteins towards specific sialylglycans. Insights in to the interactions of viral proteins with
the cell surface oligosaccharides are gained using Molecular Dynamics simulations. A recent study
on Influenza virus’ specificity towards Sialyldisaccharides revealed the details about Hemagglutinin
binding to the cell surface sialyldisaccharides.
Protein and genome sequences are analysed using in-house developed programs.
3. Polymer Physics
Natural polymers are analysed for their tensile strength and novel properties
4. Energy Physics